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Nutritional Genomics Specialist, Founder and CEO

Dr. Valentini Konstantinidou

Dr. Valentini Konstantinidou obtained her doctorate degree (PhD) in Biomedicine from Pompeu Fabra University in Barcelona, Spain (2010) and her official Master in Biomedical Research from the same University (2007). In an early, young age, she was awarded the Leonardo da Vinci fellowship (European Union) for pre-graduate studies to perform research practical training in the Institute for Medical Research, IMIM, in Barcelona. She was also awarded the I.K.Y. (Greece) scholarship to perform her post-graduate studies abroad.

During her doctorate and post-doctorate studies she specialized in the nutrigenomics and nutrigenetics effects of Mediterranean diet and virgin olive oil consumption in humans with the aim of preventing complex diseases, such as cardiovascular diseases, through lifestyle and dietary interventions. The first results of her studies have been pioneer and innovative results in the nutritional genomics field attracting international media attention.

 

She has participated in national and international competitive research projects and she has collaborated and worked with worldwide first-class experts and researchers. She is an official member of the European Lifestyle Medicine Organization, ELMO Ambassador in Spain and member of the American Society of Nutrition. Performing cutting-edge research and offering the society evidence-based scientific knowledge has always been her priority and commitment.

 

She is the author of numerous original scientific articles and her scientific results have been presented in a wide range of Congresses and Symposiums. She is deeply interested in science dissemination and she regularly publishes articles for the general public in magazines, free press and blogs. She presents a unique combination of scientific knowledge and enterprising life-science professional skills with the ability to convert scientific results into everyday practice. She is a certified coach in life coaching by Athens Coaching Institute and she is currently completing her studies in the international prestigious school Noble-Manhattan to obtain her diploma as a Practitioner Coach.

She lives in and in-between her two beloved cities: Barcelona and Athens.

Publications

For original scientific publications press here.

Main oral and poster presentations in National and International Scientific Congress are listed below:

  • “Functional Olive Oils Functions” in European Atherosclerosis Society (EAS) Congress 2014 31/05-03/06/2014, Madrid, Spain
  • MIR-107, a dietary modified microRNA (miRNA) that regulates the circadian system” in European Atherosclerosis Society (EAS) Congress 2014 31/05-03/06/2014, Madrid, Spain
  • miR-107: a metabolically relevant microRNA regulated by lipids, Atorvastatin and Fenofibrate” in Nutrigenomics Organization (NUGO) WEEK 09/09-12/09/2013 Freising, Germany
  • “Los ácidos grasos poli-insaturados, especialmente el DHA, modifican el patrón de expresión de microRNAs principalmente implicados en funciones neurológicas en un modelo de enterocito” in XXVI Congreso Nacional de la Sociedad Española de Arteriosclerosis (S.E.A), 22/05-25/05/2013, Zaragoza, Spain
  • “PUFAs, specifically DHA, modify the microRNA pattern of the enterocytes: a screening ofdiet-modified microRNAs” in the Phenotypic Flexibility Symposium, 04-06/02/2013, El Escorial, Community of Madrid, Spain
  • “Protection of LDL from oxidation by olive oil polyphenols is associated with a down-regulation of CD40L expression and its downstream products in vivo in humans”, in 25 Congreso Nacional de la Sociedad Española de Arteriosclerosis 06-08/06/2012, Reus, Spain
  • “Human transcriptome response after Mediterranean Diet consumption”, IV ISNN (International Society of Nutrigenomics/Nutrigenetics) Congress 17-20/11/2010, Pamplona, Spain
  • “In vivo nutrigenomic effects of olive oil polyphenols on atherosclerosis-related genes in humans. A randomized, controlled, clinical trial” in the International Symposiym on New Frontiers in Obesity and Nutrition 25-27/11/2009, La Toja, Galicia, Spain
  • “Nutrigenomics in vivo effects of the Mediterranean diet and virgin olive oil consumption in humans”, in the European EPIC Conference on Nutrition, Lifestyle and the Prevention of Obesity and Chronic Diseases 22-23/10/2009, Barcelona, Spain
  • “Nutrigenomic studies on Mediterranean diet and olive oil consumption” in the 14th European Congress on Biotechnology 13-16/09/2009, Barcelona, Spain
  • “Gene expression profile changes in human mononuclear cells after virgin olive oil consumption” in the 6th European Federation of Lipids Congress, 07-10/09/2008, Athens, Greece
  • “Resveratrol disposition in humans” in Wine Active Compounds WAC 2008, 26-30/03/2008, Beaune, France
  • “Human in vivo nutrigenomic effect of olive oil”, Nutrigenomics 2008, International Society of Antioxidant in Nutrition and Health ISANH 14/03/2008, Paris, France
  • “Efectos Nutrigenómicos, in vivo, del aceite de oliva virgen en humanos”, in CIBER, Fisiopatología de la Obesidad y Nutrition, I Symposium, 11/2007, Santiago de Compostela, Spain
  • “Applications of Fourier Transform Infra-red Spectroscopy to edible oils”, in the 4th International Conference in Instrumental Methods of Analysis (I.M.A), 02-06/10/2005, Crete, Greece
  • “Comparative studies on the total pro- and antioxidant activities of edible oils using Chemiluminescence”, in the 3rd Aegean Analytical Chemistry Days, 29/09-03/10/2002, Lesbos, Greece

Teaching

  • Universidad Rey Juan Carlos, Madrid, Spain in Master Oficial “Obesidad y sus comorbilidades, prevención, diagnostico y tratamiento integral”, (in Spanish)
  • Universidad de Alcalá, Madrid, Spain in Master Oficial “Obesidad y sus comorbilidades, prevención, diagnostico y tratamiento integral”, (in Spanish)
  • Universidad Autónoma de Madrid, Madrid, Spain in Practical training tutorials, (in Spanish and in English)
  • IMDEA Food Foundation, Madrid, Spain, in the Nutritional Genomics and Personalized Nutrition course (in Spanish)
  • Universitat Rovira i Virgili, Faculty of Medicine, ¨Aplicacion del we 2.0 a la docencia¨ (in Spanish)
  • Fundation Parc de Recerca Biomedica de Barcelona (PRBB) in Open Days Organization and tutorials (in Spanish and in English)
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Dr. Maria Isabel Covas, Nuproas HB

Dr. Maria-Isabel Covas owns a PhD in Biochemistry and she is specialist in Clinical Chemistry. Dr. Maria-Isabel Covas has been Head of the Cardiovascular Risk and Nutrition Research Group of the Research Institute Hospital del Mar (IMIM), (www.imim.es) in Barcelona, Spain until 2013.She has also served as Head of a Research Group in the CIBER of Physiopathology of Obesity and Nutrition (CIBEROBN), a Spanish Network of Excellence and as Deputy Head of the Clinical Laboratories in Hospital del Mar and Hospital de la Esperanza both in Barcelona, Spain.

Dr. Maria-Isabel Covas has been the Principal Investigator in more than 15 competitive national and international fund-rising calls and she is author of more than 200 original scientific articles published in indexed, peer-reviewed journals. She was the coordinator of the European Study: ¨The effect of olive oil on oxidative damage in European populations, The EUROLIVE Study¨ (QLK1-CT-2001-00287) funded under the European FP5 Program (2002-2006). The EUROLIVE study resulted in an EFSA health claim regarding olive oil phenolic compounds consumption and protection of human LDL from oxidation. She has also been the Area Coordinator and member of the Steering Committee of the PREDIMED Study (www.predimed.es),the first intervention study that proved the effect of the traditional Mediterranean diet on the primary prevention of cardiovascular disease.

She is the Scientific Advisor of NUPROAS HB a Swedish company focused on providing the best assessment and services for achieving nutritional goals related to the improvement of health. NUPROAS HB offers assessment to all kind of nutritional studies with the profound interest of translating good and original ideas into tangible and successful projects. NUPROAS HB collaborates with exceptional scientists to offer first class assistance for research protocols development, monitoring of intervention studies and statistical analysis performance.

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Dr. Elena Giordano

Dr. Elena Giordano obtained a B.Sc.Hons. in Biological Sciences at the University of Cagliari, Italy (2003) and she undertook her PhD studies in the Department of Experimental Biology at University of Cagliari, Italy (2007). Elena obtained a PhD in Morphological Science, with a thesis in Nutritional Biochemistry and Physiology in 2011. As part of her PhD training, she had the opportunity to work at the Food Science Department of Rutgers University, NJ, (USA), where she was able to develop her skills and abilities in the field of molecular biology and physiology and to study gene-nutrient interactions and modulation of gene expression by different nutrients.

 

In October 2011 Elena joined IMDEA Food in Madrid, and she worked with Prof. Francesco Visioli at the Functional Food section, as Postdoctoral Fellow, co-funded by the Amarout-Marie Curie European Programme, until December 2013. Elena led two main research projects in the field of gene-nutrient interactions, (specifically polyphenols of the Mediterranean diet) associated to cardiovascular diseases, obesity and osteoporosis. The “Marie Curie Amarout” fellowship gave her the opportunity to develop her ideas in nutritional biochemistry, nutrigenomics and metabolism. Elena’s current job as a nutritionist has enabled her to develop valuable and transferable skills into practical and evidence-based advice, including customized recipes to improve wellbeing, health and life quality. As part of her private work she provides full nutritional screening, through questionnaires, anthropometric measurements, Bioelectrical impedance analysis (BIA), Tanita scale and nutrigenetic tests for highly personalized nutritional plans, based on genetic information, lifestyle, socio-economic background, food and nutrient deficiencies.

 

Publications

  • Giordano E, Dávalos A, Crespo C, Tomé-Carneiro J, Visioli F. Soy isoflavones – in nutritionally relevant amounts – have varied nutrigenomic effects on adipose tissue. Molecules 2015 Jan 30;20(2):2310-22.
  • Giordano E, Dávalos A, Visioli F.Chronic hydroxytyrosol feeding modulates glutathionemediatedoxido- reduction pathways in adipose tissue: A nutrigenomic study. Nutr Metab Cardiovasc Dis 2014 Oct;24(10):1144-50
  • Gil-Zamorano J, Martin R, Daimiel L, Richardson K, Giordano E, Nicod N, García- Carrasco B, Soares SM, Iglesias-Gutiérrez E, Lasunción MA, Sala-Vila A, Ros E, Ordovás JM, Visioli F, Dávalos. Docosahexaenoic acid modulates the enterocyte Caco-2 cell expression of microRNAs involved in lipid metabolism. A. J Nutr. 2014 May;144(5):575-85.
  • Carta G, Murru E, Cordeddu L, Ortiz B, Giordano E, Belury MA, Quadro L, Banni S. Metabolic Interactions between Vitamin A and Conjugated Linoleic Acid. Nutrients. 2014 Mar 24;6(3):1262-72.
  • Giordano E, Visioli F. Long-chain omega 3 fatty acids: Molecular bases of potential antioxidant actions . Prostaglandins Leukot Essent Fatty Acids 2014 Jan; 90(1):1-4.
  • Giordano E, Davalos A, Nicod N, Visioli F. Hydroxytyrosol attenuates tunicamycin-induced endoplasmic reticulum stress in human hepatocarcinoma cells. Mol Nutr Food Res 2013 58:954-62
  • Auñon-Calles D, Giordano E, Bohnenberger S, Visioli F. Hydroxytyrosol is not genotoxic in vitro (2013) Pharmacol Res.
  • Banni S, Carta G, Murru E, Cordeddu L, Giordano E, Marrosu F, Puligheddu M, Floris G, Asuni GP, Cappai AL, Deriu S, Follesa P. Vagus nerve stimulation reduces body weight and fat mass in rats (2012) PLoS One. 7(9)
  • Visioli F, Giordano E, Nicod N, Davalos A. Molecular targets of omega-3 and conjugated linoleic fatty acids – “micromanaging” cellular response (2012) Frontiers in Physiology. 3:42
  • Giordano E, Banni S, Quadro L. A single dose of c9,t11 or t10,c12 conjugated linoleic acid isomers perturbs vitamin A metabolism in mice (2011) Nutr Res. 31(11):855-62.
  • Banni S, Carta G, Murru E, Cordeddu L, Giordano E, Sirigu A, Kjetil B, Vik H, Maki K C, Di Marzo V, Griinari M. (2011) Krill oil significantly decreases 2 arachidonoylglycerol plasma levels in obese subjects. Nutr. Metab. 8:7
  • Banni S, Montisci R, Sanfilippo R, Finco G, Sanna D, Giordano E, Murru E, Cordeddu L, Carta G, Banni D, Marchi A. (2010) Physiological response to lipid peroxidation in ischemia and reperfusion during carotid endarterectomy. Lipids Health Dis. 21;9:41
  • Di Marzo V, Griinari M, Carta G, Murru E, Ligresti A, Cordeddu L, Giordano E, Murru E, Bisogno T, Collu M, Batetta B, Uda S, Berge K, Banni S. (2010) Dietary krill oil increases docosahexaenoic acid and reduces 2-arachidonoylglycerol but not N-acylethanolamine levels in the brain of obese Zucker rats. Int. Dairy J. 20, 231, 235.
  • Pintus S, Pintus P, Pistis D, Batetta B, Accossu S, Uda S, Carta G, Murru E, Cordeddu L, Vacca C, Sirigu A, Giordano E, Ghiani E, Vona G, Mele M, Secchiari P, Banni S. (2010) Impact of dairy products on human nutrition: Role of the lipid fraction. Ped. Med. Chir. 32: 136-138.
  • Batetta B, Griinari M, Carta G, Murru E, Ligresti A, Cordeddu L, Giordano E, Sanna F, Bisogno T, Uda S, Collu M, Bruheim I, Di Marzo V, Banni S. Endocannabinoids may mediate the ability of (n-3) fatty acids to reduce ectopic fat and inflammatory mediators in obese Zucker rats. (2009) J Nutr. 139(8):1495-501.
  • Bolognesi C, Nucci MC, Colacci AM, Grilli S, Ippoliti F, Mucci N, Spica VR, Barbieri A, Canitano N, Chiozzotto D, Di Renzo L, Giordano E, Horn W, Roggieri P, Risi A, Silingardi P, Vaccari M, Violante FS. Biomonitoring of nurses occupationally exposed to antineoplastic drugs: the IMEPA Project. (2005) Epidemiol Prev. 29(5-6 Suppl):91-5. Italian.
  • Stensmyr MC, Giordano E, Balloi A, Angioy AM, Hansson BS. Novel natural ligands for Drosophila olfactory receptor neurones. (2003) J Exp Biol. 206 (Pt 4):715-24
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Dietist-Nutritionist, Nutrition and Metabolism Expert

Dr. Blanca Ribot

Dr. Blanca Ribot obtained her degree in Human Nutrition and Dietetics from the Rovira i Virgili University (Spain) in 2006. She continued her studies with a Master in Nutrition and Metabolism at the same University (2009), while she was conducting her doctorate thesis in the Department of Basic Medical Sciences at the University Rovira i Virgili. Dr. Ribot defended her doctoral thesis in 2012 entitled “Iron status of the mother in relation to their initial levels and the pattern of iron supplementation. Effect on the mother and newborn’s health”. She received an international mention and a Excellent Cum Laude grade. As part of her PhD training she had the opportunity to spend a period of six months at the research center Children’s Hospital Oakland Research Institute (CHORI), in California (United States).

 

Since 2007 she has been working as a professor at the degree in Human Nutrition and Dietetics at the Rovira i Virgili University and also in the Master in Nutrition and Metabolism. Since 2013 she is a postdoctoral researcher in the Nutrition and Mental Health (NUTRISAM) research group led by Prof. Victoria Arija and Prof. Josepa Canals. Dr. Ribot has published several articles in scientific, indexed peer-reviewed journals, and has presented her research results in numerous congresses. She is combining her research work with the one of dietitian in mass catering where she is monitoring the menus of the center, elaborating special diets and giving nutritional advice to professionals who request it.

 

Dr. Ribot is collegiate in the Official College of Nutritionists-Dietitians of Catalunya (Spain) (nº. CAT000155) and she is working in private practice, performing nutritional and anthropometric assessments from which elaborates customized diets and promotes an optimal state of health.

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Dietist-Nutritionist, specialized in Atherosclerosis

Aggeliki Ioannidi, MSc

Aggeliki Ioannidi obtained her degree in Science of Dietetics and Nutrition from Harokopio University of Athens, Greece (2008). She continued her education into a Master of Science degree in Clinical Nutrition (2011) and she has specialized in the nutrition of atherosclerosis patients. She has participated in national and international conferences and congresses. She is member of Hellenic Dietetics Association (HAD) and member of Hellenic Atherosclerosis Society.

She is a freelance health professional based in Athens and she has already attended more than 1000 individuals.

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Psicóloga Clínica

Natalia Molina Álvarez

Natalia Molina está licenciada en Psicología Clínica y Criminología por la Universidad de Barcelona (1986)  y colegiada en el Colegio de Psicólogos de Cataluña (COPC, No 18336).

 

Ha realizado el postgrado en Mediación Familiar, por la Fundación Doctor Robert (Universidad Autónoma de Barcelona) y se ha formado en diversas áreas de las terapias complementarias como la Terapia Breve Estratégica, como en el Desarrollo Personal Life-Coaching por el COPC, aportando el valor añadido diferencial como Coach que puede aportar a la praxis en los diversos ámbitos de intervención. Tiene formación en TIPI (Terapia de identificación Sensorial de los miedos inconscientes) y en Hipnosis.

 

También, Natalia Molina tiene amplia experiencia laboral como Psicoterapeuta y durante un largo periodo ha participado y coordinado estudios nutricionales de intervención en el Instituto Municipal de Investigación Médica (IMIM) en Barcelona, siendo el más representativo el estudio español PREDIMED (Prevención con la Dieta Mediterránea) así como otros relacionados con la Salud.