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Colorectal Cancer and microbiome: a EU-funded consortium

Colorectal Cancer and microbiome: a EU-funded consortium

  • 24 June 2024

PerMiCCion is a strategic research alliance of world-leading researchers funded by the European Union, the German Government, and led by Prof. Gianni Panagiotou.

What is PerMiCCion consortium?

PerMiCCion stands for: A Personalized Microbiome-Based Approach to Early Onset Colorectal Cancer (CRC) Prevention, Diagnosis, and Management. Here, you can read more about CRC and nutrition. This consortium brings together selected Industrial partners with prestigious research teams in the field to identify microbiome biomarkers for diagnosis and therapeutic monitoring of early-onset CRC.

Westernization of diets, synthetic food dyes, physical inactivity, and sedentary behavior, are among the key risk factors that may lead to colorectal cancer development. The gut microbiota, i.e. the microorganisms that live in our gut in symbiosis, is at the intersection of early-onset CRC and those risk factors and can be seen as a dynamic living sensor of any change in the human body.

DNANUTRICOACHas an industrial partner.

We, at DNANUTRICOACH, we are 1 out of 4 selected EU SMEs (Small and Medium Enterprises) that we join forces to apply personalized microbiome-based approaches to help in the early detection, monitoring, treatment, and prevention of colorectal cancer (CRC). We are glad and honored to participate in this huge and high-impact EU-funded project as an industrial partner.

What is the goal of the consortium?

PerMICCion´s goal is to identify how we could use the information on the microorganisms that live within our gut microbiome to develop more targeted and effective strategies for the prevention, diagnosis, treatment, and improvement of the quality of life of young colorectal cancer patients. We are well aware of how the food that we eat, our physical activity or sedentarism together with other lifestyle habits can put us at a higher risk of developing colorectal cancer, a multifactorial, complex disease.

Since the launch of this collaborative project in May 2022, Dr. Gianni Panagiotou and the scientists involved in PerMiCCion have been meeting regularly via video conferencing to set up the project’s first steps that have already led to prestigious research publications. The ultimate aim of the consortium is to develop a microbiome GPS (mGPS) that could inform patients about their microbiome positioning concerning CRC signature and the healthy gut microbiome, as well as provide personalized dietary and lifestyle choices to restore a healthy microbial gut ecosystem that would improve their quality of life.

DNANUTRICOACH´s role will be to assist in the clinical application of microbiome-based interventions with prophylactic and therapeutic potential for all.

Stay tuned for more exciting news to come.



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